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Photoreceptor axons play hide and seek

Nature Neuroscience volume 8, pages 401–402 (2005)Cite this article

The outer photoreceptors of Drosophila project to their targets in an extremely intricate pattern. Prakash et al. in this issue show that homophilic adhesion via N-cadherins is an essential part of the axon guidance mechanism in this system. The new results suggest that axons respond to the level of N-cadherins, and not to any combinatorial cadherin code, as had been postulated previously.

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Figure 1: The six outer photoreceptor cells (R1–6) from one ommatidium project to six different cartridges in the lamina (gray).

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Authors and Affiliations

  1. Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, 10003, New York, USA

    Javier Morante & Claude Desplan

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  1. Javier Morante
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  2. Claude Desplan
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Morante, J., Desplan, C. Photoreceptor axons play hide and seek. Nat Neurosci 8, 401–402 (2005). https://doi.org/10.1038/nn0405-401

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