Neurons in the mammalian master clock can maintain circadian rhythms in isolation, but must synchronize to function as a time-keeping system. A new study finds that gap junctions between neurons promote synchronous electrical activity and rhythmic behavior.
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References
Reppert, S.M. & Weaver, D.R. Nature 418, 935–941 (2002).
Welsh, D.K., Logothetis, D.E., Meisterm, M. & Reppert, S.M. Neuron 14, 697–706 (1995).
Long, M.A., Jutras, M.J., Connors, B.W. & Burwell, R.D. Nat. Neurosci. 8, 61–66 (2004).
Connors, B.W. & Long, M.A. Annu. Rev. Neurosci. 27, 393–418 (2004).
Reppert, S.M. & Schwartz, W.J. J. Neurosci. 4, 1677–1682 (1984).
Bouskila, Y. & Dudek, F.E. Proc. Natl. Acad. Sci. USA 90, 3207–3210 (1993).
Jiang, Z.G., Yang, Y.Q. & Allen, C.N. Neuroscience 77, 1059–1066 (1997).
Colwell, C.S. J. Neurobiol. 43, 379–388 (2000).
Shirakawa, T., Honma, S., Katsuno, Y., Oguchi, H. & Honma, K.I. Eur. J. Neurosci. 12, 2833–2838 (2000).
Michel, S. & Colwell, C.S. Chronobiol. Int. 18, 579–600 (2001).
Rash, J.E., Yasumura, T., Dudek, F.E. & Nagy, J.I. J. Neurosci. 21, 1983–2000 (2001).
Pennartz, C.M.A., de Jeu, M.T.G., Bos, N.P.A., Schaap, J. & Geurtsen, A.M.S. Nature 416: 286–290 (2002).
Hatton, G.I. Annu. Rev. Neurosci. 20, 375–397 (1997).
Liu, C. & Reppert, S.M. Neuron 25, 123–128 (2000).
Shinohara, K., Hiruma, H., Funabashi, T. & Kimura, F. Neuroscience 96, 591–596 (2000).
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Colwell, C. Bridging the gap: coupling single-cell oscillators in the suprachiasmatic nucleus. Nat Neurosci 8, 10–12 (2005). https://doi.org/10.1038/nn0105-10
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DOI: https://doi.org/10.1038/nn0105-10
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