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Dopamine: should I stay or should I go now?

Nature Neuroscience volume 7, pages 1019–1021 (2004)Cite this article

In C. elegans, dopamine signaling regulates locomotion behavior. Chase and colleagues report that this signaling occurs through extrasynaptic and antagonistically acting receptors coexpressed in motor neurons. These results provide surprising insights into the G-protein pathways mediating this antagonism, with implications for dopamine signaling across species.

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Figure 1: Dopamine regulation in a cholinergic motor neuron in C. elegans.
Figure 2: Model for Gαq and Gαo pathways in the nematode.

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  1. Department of Biology and the Brain Institute, University of Utah, Salt Lake City, 84112, Utah, USA

    Erik M Jorgensen

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  1. Erik M Jorgensen
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Jorgensen, E. Dopamine: should I stay or should I go now?. Nat Neurosci 7, 1019–1021 (2004). https://doi.org/10.1038/nn1004-1019

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