Abstract
Some neurons in auditory cortex respond to recent stimulus history by adapting their response functions to track stimulus statistics directly, as might be expected. In contrast, some neurons respond to loud sounds by adjusting their response functions away from high intensities and consequently remain sensitive to softer sounds. In marmoset monkey auditory cortex, the latter type of adaptation appears to exist only in neurons tuned to stimulus intensity.
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Acknowledgements
We thank K. Kocher for assistance with animal training and D. Oakley for assistance with software programming. This work was supported by the McDonnell Center for Higher Brain Function, the Wallace H. Coulter Foundation and US National Institutes of Health grant DC008880.
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D.L.B conceived of the experiment, D.L.B. and P.V.W. designed the experiment, P.V.W. collected and analyzed the data and D.L.B. wrote the paper.
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Supplementary Figures 1 and 2 and Supplementary Methods (PDF 163 kb)
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Watkins, P., Barbour, D. Specialized neuronal adaptation for preserving input sensitivity. Nat Neurosci 11, 1259–1261 (2008). https://doi.org/10.1038/nn.2201
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DOI: https://doi.org/10.1038/nn.2201
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