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Nature Neuroscience 10, 937 - 938 (2007)
doi:10.1038/nn0807-937
Nicotinic receptor structure emerging slowly
Titia K Sixma1
- Titia K. Sixma is at the Department of Molecular Carcinogenesis, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. e-mail: t.sixma@nki.nl
Abstract
A high-resolution crystal structure of the ligand-binding domain of the human nicotinic acetylcholine receptor
subunit, with three point mutations to improve its crystallization, provides both reassurance and exciting new insights.
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