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Nature Neuroscience 10, 937 - 938 (2007)
doi:10.1038/nn0807-937

Nicotinic receptor structure emerging slowly

Titia K Sixma1

  1. Titia K. Sixma is at the Department of Molecular Carcinogenesis, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. e-mail: t.sixma@nki.nl


A high-resolution crystal structure of the ligand-binding domain of the human nicotinic acetylcholine receptor alpha subunit, with three point mutations to improve its crystallization, provides both reassurance and exciting new insights.

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