Supplementary information
From the following article
Reversal of neurosteroid effects at 
4
2
GABAA receptors triggers anxiety at puberty
Hui Shen, Qi Hua Gong, Chiye Aoki, Maoli Yuan, Yevgeniy Ruderman, Michael Dattilo, Keith Williams & Sheryl S Smith
Nature Neuroscience 10, 469 - 477 (2007) Published online: 11 March 2007
doi:10.1038/nn1868
Supplementary Fig. 1
GABA concentration-response relationships and THP administration.
Supplementary Fig. 2
THP inhibition of outward current is dependent upon GABA concentration.
Supplementary Fig. 3
Pharmacological changes in the tonic inhibitory current of CA1 hippocampus are consistent with increased expression of 4 receptors after the onset of puberty.
Supplementary Fig. 4
THP increases the input resistance of hippocampal pyramidal cells at the onset of puberty.
Supplementary Table 1
ANOVA – F Tables – recombinant receptor experiments.
Supplementary Table 3
Tukey's test—planned post-hoc comparisons. Mutations, 1 
M GABA.
Supplementary Table 4
Tukey's test—planned post-hoc comparisons. Mutations, 10 M GABA.
Supplementary Table 11
Cell-attached spiking, Tukey's test—planned post-hoc comparisons.
Supplementary Table 13
Holm-Sidak post-hoc comparison.
Supplementary Table 15
Least significant difference planned post-hoc comparisons.
Supplementary Methods
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