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Nature Neuroscience 10, 403 - 404 (2007)
doi:10.1038/nn0407-403

Disrupting addiction through the loss of drug-associated internal states

John A Dani1 & P Read Montague1

  1. The authors are in the Department of Neuroscience, Menninger Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA. e-mail: jdani@bcm.tmc.edu


Damage to the insula enables some smokers to quit easily and without relapse, reports a recent paper. The lesion may disrupt a a representation of internal bodily urges that is normally cued by learned drug associations.

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