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Olfactory identity kicked up a NOTCH

A new study shows that the identity of olfactory sensory neurons in flies is regulated by Notch signaling, which divides the neurons into two classes that express specific sets of olfactory receptors and project to distinct glomeruli.

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Figure 1: The olfactory neurons within a sensillum are related by lineage and acquire their different identities through differential activation of Notch.

Kimberly Caesar

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Fuss, S., Çelik, A. & Desplan, C. Olfactory identity kicked up a NOTCH. Nat Neurosci 10, 138–140 (2007). https://doi.org/10.1038/nn0207-138

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