Brief Communication abstract


Nature Neuroscience 10, 1404 - 1406 (2007)
Published online: 14 October 2007 | doi:10.1038/nn1983

A temporal frequency–dependent functional architecture in human V1 revealed by high-resolution fMRI

Pei Sun1, Kenichi Ueno1, R Allen Waggoner1, Justin L Gardner1,2, Keiji Tanaka1 & Kang Cheng1

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Although cortical neurons with similar functional properties often cluster together in a columnar organization, only ocular dominance columns, the columnar structure representing segregated anatomical input (from one of the two eyes), have been found in human primary visual cortex (V1). It has yet to be shown whether other columnar organizations that arise only from differential responses to stimulus properties also exist in human V1. Using high-resolution functional magnetic resonance imaging, we have found such a functional architecture containing domains that respond preferentially to either low or high temporal frequency.

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  1. Laboratory for Cognitive Brain Mapping, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
  2. Center for Neural Science and Department of Psychology, New York University, 6 Washington Place, New York, New York 10003, USA.

Correspondence to: Pei Sun1 e-mail: psun@brain.riken.jp

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