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The robust anion framework of ionic nanocrystals impedes shape change by cation exchange. Here, the authors report an anisotropic, regenerative transformation of Cu1.8S nanoplates during cation exchange.
Recently, studies have identified different low-density lipoprotein receptors as functional entry receptors for alphaviruses. In this Perspective, the authors compare the known alphavirus-receptor structures and discuss why it might be challenging to generate a broad-spectrum entry inhibitor.
Synthetic biology applications require finely tuned gene expression, often mediated by synthetic transcription factors. Here the authors validate two plant-derived proteins, FHY1 and FHL, acting as transactivators in mammalian cells for orthogonal, modular, and tunable control of gene transcription by forming a photosensing transcriptional regulation complex with PhyA.
While synthetic active matter research has concentrated on developing point-like, interacting entities, designing freely jointed active assemblies from autonomously powered components has remained a challenge. Here, the authors introduce freely jointed active polymers created from self-propelled droplets, uncovering emergent rigidity and propulsion, thereby advancing towards self-morphic synthetic materials.
By performing a tissue-specific transcriptome analysis, Zhang et al. show how age-related loss of germline stem/progenitor cells in C. elegans is regulated by a signal produced by non-niche cells within the same organ system.
Developing artificial leaves is crucial for advancing Net Zero Future, but most artificial leaves rely on the use of metal or semiconductors catalysts that usually have a lower catalytic activity and selectivity compared to biocatalysts. Here the AUs report Ecoleaf, a biodegradable artificial leaf that mimics the controlled expansion and contraction of stomata and enables enzymic CO2 conversion.
Biological computing is a promising field with potential applications in biosafety, environmental monitoring, and personalized medicine. Here the authors create bio-computers using engineered E. coli colonies that respond to chemical gradients, producing different logic functions depending on how they are spatially arranged.
This study reports the genomics- and metabolomics-guided discovery of aminovinyl-(methyl-)cysteine-containing peptides (ACyP). One of these peptides, massatide A, demonstrates excellent activity against drug-resistant gram-positive pathogens.
Here, the authors develop a microfabrication method to realize the optical observation of quantum coherence and interference of a single moiré exciton in twisted semiconducting heterobilayers of transition metal dichalcogenides, persisting beyond 10 ps.
Hydrogels capable of swift mechanical energy dissipation are desirable for various uses, but traditional energy absorption in hydrogels typically relies on viscoelastic mechanisms and often suffers from slow recovery. Here, the authors report a hydrogel design harnessing molecular friction to achieve efficient energy dissipation and rapid recovery.
The realization of intrinsically stretchable organic photovoltaics with excellent mechanical robustness remains challenging. Here, the authors redistribute the strain in the active layer to PEDOT:PSS electrodes with simultaneously enhanced stretchability and interfacial adhesion in the device.
Excitation energy transfer is important for many photoinduced biological processes in systems with multiple chromophores. Here, the authors elucidate this process for the coenzyme NADH using ultrafast spectroscopy and quantum dynamics.
Efficient base editors for direct thymine (T) editing are highly desirable. Here, authors develop two deaminase-free glycosylase-based base editors for direct T editing (gTBE) and C editing (gCBE) by rounds of structure-informed mutagenesis on human DNA glycosylase UNG and further engineering.
Topological waves and their exotic properties are attracting intense research interest. Here, the authors report on the discovery of supertoroidal electromagnetic pulses with robust skyrmionic topology that persists upon propagation over arbitrarily long distances.
Creating highly active materials that effectively harness solar spectra is essential for photocatalysis, though challenging. Here the authors introduce a novel donor-acceptor covalent organic framework with a broad absorption range of 200 nm to 900 nm, achieving efficient artificial photocatalytic amine coupling.
Aligned collagen I is associated with the emergence of leader cells that are responsible for collective invasion. Here, the authors show that Collagen I and Yap signalling are in a feed-forward loop to drive the collective invasion of basal-like tumour cells.
Brain evolution at the cellular level is understudied. Here, the authors compare olfactory circuits from three Drosophila species, finding species-specific connectivity patterns associated with food odours and suggesting that more connectivity may be related to learning performance.