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Néel spin-orbit torques arise due to charge currents in some antiferromagnets, and have sparked interest as a possible pathway for achieving electrical control of antiferromagnetic order. While the driving of antiferromagnetic order by Néel spin-orbit torques is now experimentally well established, the inverse process, where magnetic excitations in an antiferromagnetic drive a charge current is not reported. Here Huang, Liao, Qiu, and coauthors observe this inverse process in an Mn2Au thin film.
Protein corona formation on the surface of liposome nanocarriers can decrease the efficiency of intracellular delivery. Here, the authors develop antifouling membrane-fusogenic liposomes for effective intracellular delivery in vivo.
Preventive interventions often require strategies to identify high-risk individuals. Here, the authors illustrate the potential utility of medical history in predicting the onset risk for thousands of diseases across clinical specialties including COVID-19.
Data-driven detection of governing rules and trends in dynamics of nonautonomous systems usually requires a significant amount of measured data. The authors propose an operator-theoretic technique for identifying trends and persistent cycles using data from a single measured trajectory, relevant for the analysis of climate dynamics.
Adhesives require a balance between cohesion and interfacial adhesion, which can be challenging to achieve. Here the authors report the polymerisation of a protic ionic liquid-based monomer, with internal and external non-covalent interactions contributing to both cohesion and adhesion.
Amino acids availability is normally a limitation for protein synthesis and can determine cancer progression and therapy response. Here, the authors show that MYC-associated cancer has a dependency on tryptophan not because of translation regulation, but Indole 3-Pyruvate synthesis.
Identifying biomarkers associated with risk of severe COVID-19 disease could inform clinical management. Here, the authors identify a long noncoding RNA associated with severe disease using data from three European countries, and validate their finding in data from Canada.
Individuals differ in how they weight probability and reward information when making risky choices. Here, the authors use magnetoencephalography to test whether such variation is related to how information is neurally represented during choice evaluation.
Traditional scintillators face challenges in achieving fast response and avoiding afterglow. Guzelturk et al. report colloidal quantum shell heterostructures with bright multiexciton emission, enabling efficient, fast, and robust scintillation for high-resolution and high-speed X-ray imaging.
Heart failure is characterised by a detrimental rise in the intracellular sodium concentration. Here the authors show that this reversibly reprogrammes energy metabolism in the heart making this a possible therapeutic target for the development of new drugs.
This study uses cryo-EM, biochemical, and computational approaches to shed light on the fundamental mechanisms underlying the human mitoribosome function, including ligand binding, modifications, Fe-S clusters, and aging-related polyamines.
Ferroptosis is a form of cell death that has been associated with different diseases. Here the authors describe an association of ferroptosis with COVID-19 pulmonary pathologies in both patient samples and hamster model and suggest that the dysregulation in iron and lipid metabolism could provide targets to reduce pathology.
Antifungal triazoles inhibit biosynthesis of ergosterol, a crucial component of the fungal plasma membrane. Here, Xie et al. show that Erg6, the enzyme that catalyzes a previous step in ergosterol biosynthesis, is essential for the viability of Aspergillus fumigatus, and its repression reduces the virulence of this fungal pathogen in an animal model of infection.
Gamma ray bursts (GRBs) are transient events and GRB 221009A was a particularly interesting event due to its brightness and duration. Here, the authors show detection of delayed 400 GeV photon from GRB 221009A, which may indicate cascade emission scenario.
Secondary bile acids are microbially produced metabolites linked to metabolic diseases. A challenge in microbiota research is to understand how bacteria collaborate to produce such bioactive molecules. Here, the authors show that adding a single low-abundance bacterial species to a community can significantly affect the metabolic output and host physiology.
The authors show that in the halophyte Salicornia the sodium transporter SOS1 localizes to the tonoplast, likely storing sodium in the vacuole. The intrinsically disordered protein SALTY, increases yeast salt tolerance possibly stabilizing ribosomes in the ER.
Genetic sex introduces variation in phenotypic traits in sexually reproducing organisms. Here, the authors report a developmental gene expression atlas for C. elegans males and hermaphrodites, highlighting the key role of the insulin-like peptide INS-39 in male development and suggesting genetic underpinnings of sexual dimorphism.
This study shows that magma rising from deep in the Earth’s mantle is not a continuous process but occurs in episodes. This is observed in East Africa with simultaneously replenishing of four magma pockets.