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Néel spin-orbit torques arise due to charge currents in some antiferromagnets, and have sparked interest as a possible pathway for achieving electrical control of antiferromagnetic order. While the driving of antiferromagnetic order by Néel spin-orbit torques is now experimentally well established, the inverse process, where magnetic excitations in an antiferromagnetic drive a charge current is not reported. Here Huang, Liao, Qiu, and coauthors observe this inverse process in an Mn2Au thin film.
Protein corona formation on the surface of liposome nanocarriers can decrease the efficiency of intracellular delivery. Here, the authors develop antifouling membrane-fusogenic liposomes for effective intracellular delivery in vivo.
Preventive interventions often require strategies to identify high-risk individuals. Here, the authors illustrate the potential utility of medical history in predicting the onset risk for thousands of diseases across clinical specialties including COVID-19.
Data-driven detection of governing rules and trends in dynamics of nonautonomous systems usually requires a significant amount of measured data. The authors propose an operator-theoretic technique for identifying trends and persistent cycles using data from a single measured trajectory, relevant for the analysis of climate dynamics.
Adhesives require a balance between cohesion and interfacial adhesion, which can be challenging to achieve. Here the authors report the polymerisation of a protic ionic liquid-based monomer, with internal and external non-covalent interactions contributing to both cohesion and adhesion.
Amino acids availability is normally a limitation for protein synthesis and can determine cancer progression and therapy response. Here, the authors show that MYC-associated cancer has a dependency on tryptophan not because of translation regulation, but Indole 3-Pyruvate synthesis.
Identifying biomarkers associated with risk of severe COVID-19 disease could inform clinical management. Here, the authors identify a long noncoding RNA associated with severe disease using data from three European countries, and validate their finding in data from Canada.
Individuals differ in how they weight probability and reward information when making risky choices. Here, the authors use magnetoencephalography to test whether such variation is related to how information is neurally represented during choice evaluation.
Traditional scintillators face challenges in achieving fast response and avoiding afterglow. Guzelturk et al. report colloidal quantum shell heterostructures with bright multiexciton emission, enabling efficient, fast, and robust scintillation for high-resolution and high-speed X-ray imaging.
This study uses cryo-EM, biochemical, and computational approaches to shed light on the fundamental mechanisms underlying the human mitoribosome function, including ligand binding, modifications, Fe-S clusters, and aging-related polyamines.
Ferroptosis is a form of cell death that has been associated with different diseases. Here the authors describe an association of ferroptosis with COVID-19 pulmonary pathologies in both patient samples and hamster model and suggest that the dysregulation in iron and lipid metabolism could provide targets to reduce pathology.
Antifungal triazoles inhibit biosynthesis of ergosterol, a crucial component of the fungal plasma membrane. Here, Xie et al. show that Erg6, the enzyme that catalyzes a previous step in ergosterol biosynthesis, is essential for the viability of Aspergillus fumigatus, and its repression reduces the virulence of this fungal pathogen in an animal model of infection.
Secondary bile acids are microbially produced metabolites linked to metabolic diseases. A challenge in microbiota research is to understand how bacteria collaborate to produce such bioactive molecules. Here, the authors show that adding a single low-abundance bacterial species to a community can significantly affect the metabolic output and host physiology.
The authors show that in the halophyte Salicornia the sodium transporter SOS1 localizes to the tonoplast, likely storing sodium in the vacuole. The intrinsically disordered protein SALTY, increases yeast salt tolerance possibly stabilizing ribosomes in the ER.
Genetic sex introduces variation in phenotypic traits in sexually reproducing organisms. Here, the authors report a developmental gene expression atlas for C. elegans males and hermaphrodites, highlighting the key role of the insulin-like peptide INS-39 in male development and suggesting genetic underpinnings of sexual dimorphism.
The authors model the transient temperature response of micro-thermoelectric devices with AC current applied, which is locally integrated under a transient hot spot. They develop a strategy for actively canceling the transient temperature variations.
NCOMMS-23-44446C Vivid structural colours in butterflies are caused by photonic nanostructures scattering light, however insight into the development of such structures in vivo remains scarce. Here the authors show that actin plays a vital and direct templating role during structural colour formation in butterfly scales, providing ridge patterning mechanisms that are likely universal across lepidoptera.
Mars, an attractive candidate for potential presence of extraterrestrial life, contains oxychlorine species such as perchlorate at its surface. Here, the authors show perchlorate brines support folding and catalysis of functional RNAs, while inactivating representative protein enzymes, and that perchlorate enables new ribozyme functions, including ribozyme catalyzed chlorination of organic molecules.
The Neolithic site of Dispilio, Northern Greece, is a pile-dwelling site with 900+ piles excavated. Here, the authors use the 5259 BC Miyake event to date the juniper tree-ring chronology constructed from these piles to 5140 BC, making it the first Neolithic site in the region to be absolutely calendar dated.