A class of proteins containing domains that are evolutionarily conserved among prokaryotes and eukaryotes was recently found to mediate post-translational AMP addition—a new protein modification called AMPylation. Similarities to the post-translational modification phosphorylation suggest that AMPylation may be an important regulatory mechanism.
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Yarbrough, M., Orth, K. AMPylation is a new post-translational modiFICation. Nat Chem Biol 5, 378–379 (2009). https://doi.org/10.1038/nchembio0609-378
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DOI: https://doi.org/10.1038/nchembio0609-378
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