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Chemo-metabolic regulation of immune responses by Tregs

Nature Chemical Biology volume 5, pages 709–710 (2009)Cite this article

Chemo-metabolic processes such as redox remodeling and amino acid availability act as immunity rheostats, revealing a new mechanism regulating intercellular cross-talk between dendritic cells, regulatory T lymphocytes and effector T lymphocytes.

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Figure 1: How Tregs can interfere with the redox-based cross-talks between dendritic and Teff cells.

Katie Vicari

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Authors and Affiliations

  1. Anna Rubartelli is in the Laboratory of Cell Biology, Istituto Nationale per la Ricerca sul Cancro, Genova, Italy. anna.rubartelli@istge.it,

    Anna Rubartelli

  2. Roberto Sitia is in the Division of Genetics and Cell Biology, Università Vita-Salute San Raffaele Scientific Institute, Milano, Italy. r.sitia@hsr.it,

    Roberto Sitia

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  1. Anna Rubartelli
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  2. Roberto Sitia
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Rubartelli, A., Sitia, R. Chemo-metabolic regulation of immune responses by Tregs. Nat Chem Biol 5, 709–710 (2009). https://doi.org/10.1038/nchembio.226

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