Crosstalk between histone modifications plays an important role in transcriptional regulation. In a recent study, an elegant chemical synthesis approach has been used to study the intricate relationship between two modifications associated with active transcription.
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Lee, N., Zhang, Y. Chemical answers to epigenetic crosstalk. Nat Chem Biol 4, 335–337 (2008). https://doi.org/10.1038/nchembio0608-335
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DOI: https://doi.org/10.1038/nchembio0608-335