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Nature Chemical Biology 4, 273–275 (1 May 2008) | doi:10.1038/nchembio0508-273

Do-it-yourself enzymes

Vikas Nanda

Each new advance in the field of protein design raises our expectations for future designs; targets that seemed impossible only ten years ago are now attainable with better computational tools. New protein folds have been built from scratch, such as a right-handed four-helix coiled coil and a novel α/β protein.