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Nature Chemical Biology 4, 226–227 (1 April 2008) | doi:10.1038/nchembio0408-226
Fast-tracking steroid receptor crystallization
Abstract
Steroid receptors are attractive drug targets because of their important biological roles as transcription factors naturally modulated by small signaling molecules. Development of drugs targeting these receptors has preceded by far a detailed understanding of the mechanisms of action of either natural or synthetic ligands.
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