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Unexpected tails of a Ca2+ sensor

Myristoylation is an important post-translational modification that targets many signaling proteins to membranes. Now the crystal structure of calcium-bound myristoylated GCAP-1 demonstrates a new structural role for protein myristoylation.

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Figure 1: The diverse roles of myristoyl tails in NCS proteins.

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Haynes, L., Burgoyne, R. Unexpected tails of a Ca2+ sensor. Nat Chem Biol 4, 90–91 (2008). https://doi.org/10.1038/nchembio0208-90

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