Recent crystal structures of a bacterial copper tolerance protein reveal an intriguing copper binding site that includes tryptophan. Its close proximity coupled with spectroscopic data suggests an unusual cation-π interaction between Cu(I) and the aromatic ring of tryptophan.
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Franz, K. Copper shares a piece of the π. Nat Chem Biol 4, 85–86 (2008). https://doi.org/10.1038/nchembio0208-85
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DOI: https://doi.org/10.1038/nchembio0208-85
