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Nature Chemical Biology 3, 243–244 (1 May 2007) | doi:10.1038/nchembio0507-243
Assembling iron-sulfur clusters in the cytosol
Abstract
Iron-sulfur ([Fe-S]) clusters, which are among the most ubiquitous and versatile metal centers in biology, require complex machinery for assembly in vivo. Key components of this machinery reside in the mitochondria, where [Fe-S] clusters are assembled on scaffold proteins for eventual transfer to target proteins.
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