Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
News and Views
Nature Chemical Biology 3, 136–137 (1 March 2007) | doi:10.1038/nchembio0307-136
Transcriptional activation by small RNA duplexes
Abstract
RNA interference (RNAi) was first described as a post-transcriptional gene silencing process triggered by small double-stranded RNAs 21 to 28 nucleotides in length. Initial reports found a role for these small RNAs in DNA methylation in plants, with subsequent experiments in Schizosaccharomyces pombe and Drosophila melanogaster providing further proof of the generality of this phenomenon and additional mechanistic insight into the process with the identification of RNAi components and methylated histones.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
