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Letter
Nature Chemical Biology 3, 763–768 (1 December 2007) | doi:10.1038/nchembio.2007.45
Dissecting metal ion|[ndash]|dependent folding and catalysis of a single DNAzyme
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Abstract
Protein metalloenzymes use various modes for functions for which metal-dependent global conformational change is required in some cases but not in others. In contrast, most ribozymes require a global folding that almost always precedes enzyme reactions.
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