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Commentary

Nature Chemical Biology 3, 2–7 (1 January 2007) | doi:10.1038/nchembio0107-2

Chemical crosshairs on the central dogma

Aseem Z Ansari

The central dogma of biology, in its simplest form, is that genomic information is transcribed to RNA, which is then translated to proteins. The 2006 Nobel Prize in Chemistry brought into focus the molecular machinery involved in transcription, the first stage of information transfer.