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Nature Chemical Biology 3, 16–17 (1 January 2007) | doi:10.1038/nchembio0107-16
'Turning on' riboswitches to their antibacterial potential
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Abstract
Drug-resistant bacteria such as strains of Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa and Mycobacterium tuberculosis (TB) present a major global challenge for the medical and pharmaceutical communities. This is especially true in Western countries, where it is feared that overprescription of antibiotics will generate a new superclass of resistant bacteria.
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