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Letter

Nature Chemical Biology 2, 153–157 (1 March 2006) | doi:10.1038/nchembio767

Analyzing the dynamic bacterial glycome with a lectin microarray approach

Ku-Lung Hsu , Kanoelani T Pilobello & Lara K Mahal

Glycosylation of bacterial cell surfaces is emerging as a critical factor in symbiosis, pathogenesis, cell-cell interactions and immune evasion. The lack of high-throughput analytical tools to examine bacterial glycans has been a major obstacle to the field and has hindered closer examination of the dynamics of carbohydrate variation.