In the brain, neurotransmitter-receptor binding represents the moment of stereochemical recognition in which one neuron senses the signal sent by another. Submillisecond time-resolved FTIR spectroscopy now provides a first glimpse of the generative protein-ligand interactions that lead to glutamate receptor ion channel activation.
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Rebecca Henretta
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Madden, D. New light on an open-and-shut case. Nat Chem Biol 1, 317–319 (2005). https://doi.org/10.1038/nchembio1105-317
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DOI: https://doi.org/10.1038/nchembio1105-317
