Iron-sulfur clusters and hemes are two iron-containing prosthetic groups involved in important physiological functions. Identification of the gene responsible for anemia in a mutant zebrafish has revealed an unexpected link between iron-sulfur cluster assembly and heme synthesis in red blood cells.
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Rouault, T. Linking physiological functions of iron. Nat Chem Biol 1, 193–194 (2005). https://doi.org/10.1038/nchembio0905-193
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DOI: https://doi.org/10.1038/nchembio0905-193
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