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Ending the prolonged life of cancer cells

The fate of cells depends on a delicate balance of pro- and anti-apoptotic proteins. Small-molecule inhibitors of anti-apoptotic protein-protein interactions promote apoptosis in cancer cells.

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Figure 1: Mechanisms of mitochondrial cytochrome c release in apoptosis.

Ivelisse Robles

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Wagner, G. Ending the prolonged life of cancer cells. Nat Chem Biol 1, 8–9 (2005). https://doi.org/10.1038/nchembio0605-8

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