The fate of cells depends on a delicate balance of pro- and anti-apoptotic proteins. Small-molecule inhibitors of anti-apoptotic protein-protein interactions promote apoptosis in cancer cells.
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Wagner, G. Ending the prolonged life of cancer cells. Nat Chem Biol 1, 8–9 (2005). https://doi.org/10.1038/nchembio0605-8
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DOI: https://doi.org/10.1038/nchembio0605-8