Volume 24
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No. 12 December 2022
Pro-angiogenic migrasomesIn the chicken embryo, monocytes foster a pro-angiogenic microenvironment in advance of angiogenesis by depositing migrasomes enriched in angiogenic factors.
See Zhang et al.
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No. 11 November 2022
SARS-CoV-2Tanaka et al. generate salivary gland organoids from human induced pluripotent stem cells that serve as a model for salivary gland development and SARS-CoV-2 infection.
See Tanaka et al.
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No. 10 October 2022
lncRNA promoter function in diabetesBeucher et al. show that the lncRNA promoter HASTER, which is antisense to HNF1A, is a cell-specific cis-regulatory element that stabilizes HNF1A through positive and negative feedback loops, and that HASTER deletion can cause diabetes.
See Beucher et al.
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No. 9 September 2022
Synthetic embryo self-assemblyBao et al. show that differential adhesion force, mediated by a stem-cell-specific cadherin code, integrates with cell cortical tension to drive morphogenesis in synthetic embryos.
See Bao et al.
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No. 8 August 2022
Mechanotransduction by spectrinAn apical spectrin network in endothelial cells transmits mechanical forces in response to shear flow-induced stress in a mechanism mediated by hyaluronic acid and PIEZO1.
See Mylvaganam et al.
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No. 7 July 2022
DevelopmentSkin homeostasis and regeneration
See Sedov et al.
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No. 6 June 2022
AgeingFat-to-neuron lipid signalling
See Savini et al.and News & Views by Brunet
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No. 5 May 2022
Lipid signallingPhosphoinositide metabolism
See Walpole et al.and News & Views by Baskin
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No. 4 April 2022
RNAThe expanding universe of small RNAs
See Shi et al.
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No. 3 March 2022
Stem cellsImmune tolerance in stem cells
See Pinho et al. and News & Views by Lengerke
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No. 2 February 2022
DevelopmentA monoastral spindle controls cell fate
See Pomp et al.
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No. 1 January 2022
TrafficImaging nuclear transport
See Chowdhury et al.