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Nature Cell Biology 9, 1346 (1 December 2007) | doi:10.1038/ncb1207-1346

Entosis: cell death by invasion

Nathalie Le Bot

Most animal cells require attachment to an extracellular matrix for survival. Within the mammary gland, death of matrix-deprived cells underlies lumen formation during development and is also thought to act as a defence against the formation of breast tumours.