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Letter
Nature Cell Biology 7, 719–723 (1 July 2005) | doi:10.1038/ncb1274
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
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Abstract
Small RNAs, including small interfering RNAs (siRNAs) and microRNAs (miRNAs) can silence target genes through several different effector mechanisms. Whereas siRNA-directed mRNA cleavage is increasingly understood, the mechanisms by which miRNAs repress protein synthesis are obscure.
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