In animal cells, cytokinesis is initiated by assembly and ingression of a cleavage furrow, the position of which is determined by signals from the anaphase spindle. Recent work highlights two specialized microtubule populations that may stimulate furrow assembly: inter-zonal microtubule bundles, and astral microtubules that are stabilized by proximity to chromosomes.
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Maddox, A., Oegema, K. Deconstructing cytokinesis. Nat Cell Biol 5, 773–776 (2003). https://doi.org/10.1038/ncb0903-773b
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DOI: https://doi.org/10.1038/ncb0903-773b
