The epithelial–mesenchymal transition (EMT) is a cellular transdifferentiation program that enables epithelial cancer cells to acquire traits of high-grade malignancy, notably invasive and metastatic powers. A new study indicates that it may also function early in tumour progression by preventing oncogene-induced senescence.
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Weinberg, R. Twisted epithelial–mesenchymal transition blocks senescence. Nat Cell Biol 10, 1021–1023 (2008). https://doi.org/10.1038/ncb0908-1021
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DOI: https://doi.org/10.1038/ncb0908-1021
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