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Letter

Nature Cell Biology 10, 1076–1082 (1 September 2008) | doi:10.1038/ncb1767

Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression

Zheng Fu , Liviu Malureanu , Jun Huang , Wei Wang , Hao Li , Jan M. van Deursen , Donald J. Tindall & Junjie Chen

Proper control of entry into and progression through mitosis is essential for normal cell proliferation and the maintenance of genome stability. The mammalian mitotic kinase Polo-like kinase 1 (Plk1) is involved in multiple stages of mitosis.