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Letter
Nature Cell Biology 10, 611–618 (1 May 2008) | doi:10.1038/ncb1724
p53 regulates glucose metabolism through an IKK-NF-|[kappa]|B pathway and inhibits cell transformation
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Abstract
Cancer cells use aerobic glycolysis preferentially for energy provision and this metabolic change is important for tumour growth. Here, we have found a link between the tumour suppressor p53, the transcription factor NF-κB and glycolysis.
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