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Letter

Nature Cell Biology 10, 1470–1476 (1 December 2008) | doi:10.1038/ncb1800

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Johan Skog , Tom W|[uuml]|rdinger , Sjoerd van Rijn , Dimphna H. Meijer , Laura Gainche , William T. Curry , Bob S. Carter , Anna M. Krichevsky & Xandra O. Breakefield

Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain microvascular endothelial cells.