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Letter
Nature Cell Biology 10, 77–84 (1 January 2008) | doi:10.1038/ncb1671
Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex
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Abstract
Satellite cells purified from adult skeletal muscle can participate extensively in muscle regeneration and can also re-populate the satellite cell pool, suggesting that they have direct therapeutic potential for treating degenerative muscle diseases. The paired-box transcription factor Pax7 is required for satellite cells to generate committed myogenic progenitors.
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