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Nature Cell Biology 1, E33 - E35 (1999)
doi:10.1038/10026

How BAD phosphorylation is good for survival

Julian Downward1

  1. Julian Downward is at the Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

Correspondence to: Julian Downward1 e-mail: downward@icrf.icnet.uk

BAD is a pro-apoptotic member of the Bcl-2 family that is tightly regulated by survival factors. Several major signalling pathways influence cell death through their direct effects on the phosphorylation state of BAD.

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