Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Facilitating T cell infiltration in tumor microenvironment overcomes resistance to PD-L1 blockade

Tang, H. et al. Cancer Cell 29, 285–296 (2016)

TarO-specific inhibitors of wall teichoic acid biosynthesis restore β-lactam efficacy against methicillin-resistant staphylococci

Lee, S.H. et al. Sci. Transl. Med. 8, 329ra32 (2016)

Rhodopsin targeted transcriptional silencing by DNA-binding

Botta, S. et al. eLife 5, e12242 (2016)

Engineered hybrid cardiac patches with multifunctional electronics for online monitoring and regulation of tissue function

Feiner, R. et al. Nat. Mater. doi:10.1038/nmat4590 (2016)

Bayesian sparse regression analysis documents the diversity of spinal inhibitory interneurons

Gabitto, M.I. et al. Cell doi:10.1016/j.cell.2016.01.026 (2016)