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Pushing the envelope on HIV-1 neutralization

Nature Biotechnology volume 28, pages 929–931 (2010)Cite this article

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The identification of broadly neutralizing monoclonal antibodies against HIV-1 may aid efforts to design a vaccine.

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Figure 1: Neutralization breadth of anti-HIV monoclonal antibodies depends on antibody-generation technology and antigen configuration.

References

  1. Wu, X. et al. Science 329, 856–861 (2010).

    Article  CAS  Google Scholar 

  2. Zhou, T. et al. Science 329, 811–817 (2010).

    Article  CAS  Google Scholar 

  3. Scheid, J.F. et al. J. Immunol. Methods 343, 65–67 (2009).

    Article  CAS  Google Scholar 

  4. Kwong, P.D. & Wilson, I.A. Nat. Immunol. 10, 573–578 (2009).

    Article  CAS  Google Scholar 

  5. Hammond, P.W. mAbs 2, 157–164 (2010).

    Article  Google Scholar 

  6. Walker, L.M. et al. Science 326, 285–289 (2009).

    Article  CAS  Google Scholar 

  7. Pancera, M. et al. J. Virol. 84, 8098–8110 (2010).

    Article  CAS  Google Scholar 

  8. Bianchi, E. et al. Proc. Natl. Acad. Sci. USA 107, 10655–10660 (2010).

    Article  CAS  Google Scholar 

  9. Bommakanti, G. et al. Proc. Natl. Acad. Sci. USA. 107, 13701–13706 (2010).

    Article  CAS  Google Scholar 

  10. Rerks-Ngarm, S. et al. N. Engl. J. Med. 361, 2209–2220 (2009).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Joseph G. Joyce and Jan ter Meulen are in the Department of Vaccine Research, Merck Research Laboratories, West Point, Pennsylvania, USA.,

    Joseph G Joyce & Jan ter Meulen

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  1. Joseph G Joyce
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  2. Jan ter Meulen
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Correspondence to Joseph G Joyce.

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Competing interests

J.G.J. and J.t.M. are employees of Merck & Co.

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Joyce, J., ter Meulen, J. Pushing the envelope on HIV-1 neutralization. Nat Biotechnol 28, 929–931 (2010). https://doi.org/10.1038/nbt0910-929

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