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Nature Biotechnology 27, 455 - 457 (2009)
doi:10.1038/nbt0509-455

How to map billions of short reads onto genomes

Cole Trapnell1 & Steven L Salzberg1


Mapping the vast quantities of short sequence fragments produced by next-generation sequencing platforms is a challenge. What programs are available and how do they work?

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  1. Cole Trapnell and Steven L. Salzberg are at the Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, USA.

Correspondence to: Cole Trapnell1Steven L Salzberg1 e-mail: cole@cs.umd.edu or salzberg@umd.edu




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