Two groups have combined padlock probes and massively parallel sequencing to characterize cytosine methylation in targeted regions of the human genome.
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P.W.L. is a Scientific Advisory Board member and consultant for Epigenomics, AG, which has a commercial interest in DNA methylation diagnostics.
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Berman, B., Weisenberger, D. & Laird, P. Locking in on the human methylome. Nat Biotechnol 27, 341–342 (2009). https://doi.org/10.1038/nbt0409-341
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DOI: https://doi.org/10.1038/nbt0409-341