Volume 26 Issue 3, March 2008
Image of color-coded tags hybridized to individual mRNA molecules and attached to a surface.The fluorescent tags consist of a single-stranded DNA scaffold annealed to a series of seven complementary in vitrotranscribed RNAs each labeled with one of four fluorophores.The linear order of the different colors defines a unique code for each gene of interest.The molecular tags are linked to gene-specific probes and used to measure directly the levels of over 500 different mRNA species in a single reaction by counting the number of times each hybridized code is detected.See Geiss et al.(p 317).
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