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Volume 24 Issue 6, June 2006

Phase contrast micrograph of microwells from arrays containing monoclonal antibody-producing hybridomas. The small volumes of the microwells (~1 nL each) in the arrays described by Love et al. ensure that the antibodies produced by single cells are detectable in only 2-4 hours, compared with the 2-7 days required using current approaches, p. 703.

Editorial

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News

  • The first ever clinical trial of a therapeutic antibody that binds to natural killer (NK) cell receptors is slated to take place before the year end.

    • Cormac Sheridan
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  • Pension managers may be warming up to the idea that much needed high rewards for their funds could come from investing in the high risk private equity biotech sector.

    • John Ransom
    News
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News in Brief

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Data Page

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News Feature

  • As equine cloning becomes a commercial reality, what will be the likely impact on the elite world of horse breeding and racing? Stephanie L. Church investigates.

    • Stephanie L. Church
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Correspondence

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Commentary

  • Even in sub-Saharan Africa's most progressive nations, agbiotech partnerships are still often poorly oriented to end users, fragmented in scope and of limited impact in achieving the United Nation's Millennium Development Goals.

    • Seife Ayele
    • Joanna Chataway
    • David Wield
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Investors Lab

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  • Although investors remained cautious of public biotech companies in 2005, acquisitions and research partnerships were on the up.

    • Riku Lähteenmäki
    • Stacy Lawrence
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  • Compared with the plethora of financial information about the publicly traded elite of the biotech world, little is known about the multitude of private biotech firms. Here, Nature Biotechnology's Editor-at-Large provides an analysis of the financial performance of the privately held biotech sector.

    • John Hodgson
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Patents

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News & Views

  • A method for amplifying DNA from single bacterial cells shows promise for complete genome sequencing.

    • Clyde A Hutchison III
    • J Craig Venter
    News & Views
  • A method for altering the substrate specificity of LuxR proteins may facilitate the engineering of artificial communication systems among cells.

    • Stephen W Michnick
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  • Unraveling how a soil-dwelling bacterium kills insects promises to deliver new biopesticides.

    • Richard H ffrench-Constant
    • Nicholas R Waterfield
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  • A new approach to reducing the immunological side effects of gene therapy exploits microRNA to knock down transgene expression in immune cells.

    • Waseem Qasim
    • Adrian J Thrasher
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  • Spermatogonial stem cells in adult testis may be more versatile than embryonic stem cells.

    • Mito Kanatsu-Shinohara
    • Takashi Shinohara
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