Nature Biotechnology
- 24, 1392 - 1401 (2006)
Published online: 19 October 2006; | doi:10.1038/nbt1259
Production of pancreatic hormone–expressing endocrine cells from human embryonic stem cellsKevin A D'Amour, Anne G Bang, Susan Eliazer, Olivia G Kelly, Alan D Agulnick, Nora G Smart, Mark A Moorman, Evert Kroon, Melissa K Carpenter & Emmanuel E Baetge Supplementary Fig. 1 (pdf 580K)
Endocrine differentiation from hES cells is critically dependent on the DE lineage. Supplementary Fig. 2a (pdf 530K)
Endocrine differentiation from hES cells via DE but not neural or extra-embryonic lineages. Supplementary Fig. 2b (pdf 525K)
Endocrine differentiation from hES cells via DE but not neural or extra-embryonic lineages. Supplementary Fig. 3 (pdf 470K)
Comparison of mRNA expression levels in hES-derived cells to fetal and adult human pancreas. Supplementary Fig. 4 (pdf 1215K)
Amylase expressing cells are intermingled with endocrine cells. Supplementary Fig. 5 (pdf 1055K)
Endocrine clusters stain with dithizone. Supplementary Fig. 6 (pdf 825K)
Numerous secretory granules in hES cell-derived cells. Supplementary Fig. 7 (pdf 540K)
Differentiation of 5 different hES cell lines to insulin-expressing cells. Supplementary Fig. 8 (pdf 1200K)
MAFB and insulin are co-expressed in hES cell-derived cells and human fetal pancreas. Supplementary Table 1 (pdf 200K)
Real-time PCR primers.
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