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Plug-and-play with RNA

Ligand-responsive riboregulators enable extracellular control of post-transcriptional gene expression.

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Figure 1: Engineered RNA switch system.

Bob Crimi

References

  1. Bayer, R.S. & Smolke, C.D. Nat. Biotechnol. 23, 337–343 (2005).

    Article  CAS  Google Scholar 

  2. Bartel, D. Cell 116, 281–297 (2004).

    Article  CAS  Google Scholar 

  3. Gottesman, S. Genes Dev. 16, 2829–2842 (2002).

    Article  CAS  Google Scholar 

  4. Mandal, M. Cell 113, 577–586 (2003).

    Article  CAS  Google Scholar 

  5. Winkler, W.C. et al. Nature 428, 281–286 (2004).

    Article  CAS  Google Scholar 

  6. Isaacs, F.J. et al. Nat. Biotechnol. 22, 841–847 (2004).

    Article  CAS  Google Scholar 

  7. Yen, L. et al. Nature 43, 471–476 (2004).

    Article  Google Scholar 

  8. Kobayashi, H. Proc. Natl. Acad. Sci. USA 101, 8414–8419 (2004).

    Article  CAS  Google Scholar 

  9. Ellington, A.D. & Szostak, J.W. Nature 346, 818–822 (1990).

    Article  CAS  Google Scholar 

  10. Tuerk, C. & Gold, L. Science 249, 505–510 (1990).

    Article  CAS  Google Scholar 

Download references

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Isaacs, F., Collins, J. Plug-and-play with RNA. Nat Biotechnol 23, 306–307 (2005). https://doi.org/10.1038/nbt0305-306

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