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| In This Issue | Top |
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| Editorial | Top |
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An impossible job p1321 doi:10.1038/nbt1105-1321 Full text | PDF
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| News | Top |
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First-in-class biologic to enter rheumatoid arthritis fray pp1323 - 1324 Ken Garber Published online: 01 November 2005 | doi:10.1038/nbt1105-1323 Abstract | Full text | PDF
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Pessimistic response to FDA leadership change p1325 Jim Kling Published online: 01 November 2005 | doi:10.1038/nbt1105-1325 Abstract | Full text | PDF
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Monsanto's Bollgard potentially compromised in India p1326 K.S. Jayaraman Published online: 01 November 2005 | doi:10.1038/nbt1105-1326 Abstract | Full text | PDF
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Sandoz sues FDA over delay in first biogeneric approval pp1327 - 1328 Jeffrey L. Fox Published online: 01 November 2005 | doi:10.1038/nbt1105-1327 Abstract | Full text | PDF
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| In Brief |
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News In Brief pp1329 - 1330Published online: 01 November 2005 | doi:10.1038/nbt1105-1329 Full text | PDF
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Profile: Eduardo Kac p1331 Stephan Herrera Published online: 01 November 2005 | doi:10.1038/nbt1105-1331 Abstract | Full text | PDF
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| Data Page |
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Biotech marks time in Q3 p1332 Stacy Lawrence Published online: 01 November 2005 | doi:10.1038/nbt1105-1332 Full text | PDF
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| News Feature |
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The search for a sequencing thoroughbred pp1333 - 1335 Jim Kling Published online: 01 November 2005 | doi:10.1038/nbt1105-1333 Abstract | Full text | PDF
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| Bioentrepreneur | Top |
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| Bioenews |
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When will Israeli biotech grow up? p1337 Alla Katsnelson Published online: 15 September 2005 | doi:10.1038/bioent882 Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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| Building a business |
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Space: the final frontier pp1339 - 1341 James J Medenbach Published online: 24 October 2005 | doi:10.1038/bioent885 Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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| Opinion and Comment | Top |
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| Correspondence |
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BiDil's impact p1343 Gary Puckrein
& Clyde W. Yancy doi:10.1038/nbt1105-1343a Full text | PDF
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Response to BiDil's impact pp1343 - 1344 doi:10.1038/nbt1105-1343b Full text | PDF
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'On-the-fly' or 'generate-first' modeling? pp1344 - 1345 Michael L. Blinov, James R. Faeder, Jin Yang, Byron Goldstein
& William S. Hlavacek doi:10.1038/nbt1105-1344 Full text | PDF
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Response to 'On-the-fly' or 'generate-first' modeling? p1345 Larry Lok
& Roger Brent doi:10.1038/nbt1105-1345 Full text | PDF
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Molecule–kinase interaction map p1346 John K. Buolamwini
& Shantaram Kamath doi:10.1038/nbt1105-1346a Full text | PDF
(112K)
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Response to Molecule–kinase interaction map pp1346 - 1348 Miles A. Fabian, William H. Biggs III, Daniel K. Treiber, Patrick P. Zarrinkar
& David J. Lockhart doi:10.1038/nbt1105-1346b Full text | PDF
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Plant transgenic science knowledge pp1348 - 1349 Philippe Vain doi:10.1038/nbt1105-1348 Full text | PDF
(117K)
| Supplementary Information |
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| Commentary |
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Why tissue engineering needs process engineering pp1353 - 1355 Richard Archer
& David J Williams doi:10.1038/nbt1105-1353 Abstract | Full text | PDF
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| Investor's Lab |
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The number on biotech indexes p1356 Tom Jacobs doi:10.1038/nbt1105-1356 Full text | PDF
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| Book Review |
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Bright new world p1357 Reviewed by: Jason Borenstein doi:10.1038/nbt1105-1357 Full text | PDF
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| Features | Top |
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The business of making vaccines pp1359 - 1366 Cormac Sheridan doi:10.1038/nbt1105-1359 Abstract | Full text | PDF
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| Patents |
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The patentability of medicinal inventions related to personalized medicine in Japan pp1367 - 1369 Itsuki Shimbo, Andrew Cobden
& Koichi Sumikura doi:10.1038/nbt1105-1367 Abstract | Full text | PDF
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Recent patent applications in antiviral vaccines p1370 doi:10.1038/nbt1105-1370 Full text | PDF
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| News and Views | Top |
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Green light for mosquito control pp1371 - 1372 Peter W Atkinson doi:10.1038/nbt1105-1371 Abstract | Full text | PDF
(159K)
See also: Research by Catteruccia et al. |
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In vivo veritas pp1372 - 1374 Laurence Zitvogel
& Thomas Tursz doi:10.1038/nbt1105-1372 Abstract | Full text | PDF
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See also: Research by de Vries et al. |
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Boolean calculations made easy (for ribozymes) pp1374 - 1376 Adam A Margolin
& Milan N Stojanovic doi:10.1038/nbt1105-1374 Abstract | Full text | PDF
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See also: Research by Penchovsky & Breaker |
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Life, diversity and the pursuit of haplotypes pp1376 - 1377 Jeanette McCarthy doi:10.1038/nbt1105-1376 Abstract | Full text | PDF
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Biofilms strike back pp1378 - 1379 George A O'Toole
& Philip S Stewart doi:10.1038/nbt1105-1378 Abstract | Full text | PDF
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A classic assembly of nanobiomaterials pp1379 - 1380 Andreas Mershin, Brian Cook, Liselotte Kaiser
& Shuguang Zhang doi:10.1038/nbt1105-1379 Abstract | Full text | PDF
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Research Highlights p1381 doi:10.1038/nbt1105-1381 Full text | PDF
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| Computational Biology | Top |
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| Analysis |
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Mapping of conserved RNA secondary structures predicts thousands of functional noncoding RNAs in the human genome pp1383 - 1390 Stefan Washietl, Ivo L Hofacker, Melanie Lukasser, Alexander Hüttenhofer
& Peter F Stadler Published online: 04 November 2005 | doi:10.1038/nbt1144 Abstract | Full text | PDF
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| Supplementary Information |
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An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets pp1391 - 1398 Daniel Schwartz
& Steven P Gygi Published online: 04 November 2005 | doi:10.1038/nbt1146 Abstract | Full text | PDF
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| Supplementary Information |
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| Research | Top |
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| Review |
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Activation of the mammalian immune system by siRNAs pp1399 - 1405 Joao T Marques
& Bryan R G Williams Published online: 04 November 2005 | doi:10.1038/nbt1161 Abstract | Full text | PDF
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| Articles |
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Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy pp1407 - 1413 I Jolanda M de Vries, W Joost Lesterhuis, Jelle O Barentsz, Pauline Verdijk, J Han van Krieken, Otto C Boerman, Wim J G Oyen, Johannes J Bonenkamp, Jan B Boezeman, Gosse J Adema, Jeff W M Bulte, Tom W J Scheenen, Cornelis J A Punt, Arend Heerschap
& Carl G Figdor Published online: 30 October 2005 | doi:10.1038/nbt1154 Abstract | Full text | PDF
(408K)
| Supplementary Information See also: News and Views by Zitvogel & Tursz |
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An Anopheles transgenic sexing strain for vector control pp1414 - 1417 Flaminia Catteruccia, Jason P Benton
& Andrea Crisanti Published online: 09 October 2005 | doi:10.1038/nbt1152 Abstract | Full text | PDF
(275K)
| Supplementary Information See also: News and Views by Atkinson |
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Cell-specific targeting of nanoparticles by multivalent attachment of small molecules pp1418 - 1423 Ralph Weissleder, Kimberly Kelly, Eric Yi Sun, Timur Shtatland
& Lee Josephson Published online: 23 October 2005 | doi:10.1038/nbt1159 Abstract | Full text | PDF
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| Supplementary Information |
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Computational design and experimental validation of oligonucleotide-sensing allosteric ribozymes pp1424 - 1433 Robert Penchovsky
& Ronald R Breaker Published online: 23 October 2005 | doi:10.1038/nbt1155 Abstract | Full text | PDF
(678K)
| Supplementary Information See also: News and Views by Margolin & Stojanovic |
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| Letters |
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Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors pp1435 - 1439 Yi Lai, Yongping Yue, Mingju Liu, Arkasubhra Ghosh, John F Engelhardt, Jeffrey S Chamberlain
& Dongsheng Duan Published online: 09 October 2005 | doi:10.1038/nbt1153 Abstract | Full text | PDF
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| Supplementary Information |
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Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency pp1440 - 1444 Volker Patzel, Sascha Rutz, Isabell Dietrich, Christian Köberle, Alexander Scheffold
& Stefan H E Kaufmann Published online: 30 October 2005 | doi:10.1038/nbt1151 Abstract | Full text | PDF
(302K)
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| Resources | Top |
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| New on the Market |
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Thermocycling & amplification p1445 doi:10.1038/nbt1105-1445a Full text | PDF
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Liquid handling p1445 doi:10.1038/nbt1105-1445b Full text | PDF
(157K)
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| Naturejobs | Top |
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| Careers and Recruitment |
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Entrepreneurs: the missing link in the training of medical scientists pp1447 - 1448 David A Shaywitz doi:10.1038/nbt1105-1447 Abstract | Full text | PDF
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| People |
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People p1450 doi:10.1038/nbt1105-1450 Full text | PDF
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