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Nature Biotechnology
ISSUE
July 2004, Volume 22 No 7
In This Issue
Editorial
NewsIn Brief | Data Page | News Feature
Opinion and CommentCorrespondence | Commentary | Investor's Lab | Book Review
Feature
News and Views
ResearchReview | Articles | Letters | Errata | Corrigenda
ResourcesPatents | People | New on the Market
Computational BiologyPrimer | Analysis
BioentrepreneurBioenews | Building a business
NaturejobsCareers and Recruitment
About the cover
In This Issue Top
PDF
Editorial Top
Numb and number p785
doi:10.1038/nbt0704-785
Full text | PDF (54K)
News Top
Celltech acquisition sends mixed messages p787
Peter Mitchell
Published online: 21 June 2004 | doi:10.1038/nbt0704-787
Full text | PDF (196K)
Genta sued over NDA withdrawal pp788 - 789
George S. Mack
Published online: 21 June 2004 | doi:10.1038/nbt0704-788
Full text | PDF (327K)
E&Y report backs Asia-Pacific biotech pp789 - 790
Sabine Louët
doi:10.1038/nbt0704-789
Full text | PDF (145K)
Agbiotech firms realign product focus p791
Jeffrey L Fox
Published online: 21 June 2004 | doi:10.1038/nbt0704-791
Full text | PDF (93K)
US rejiggers Bioshield bill p792
Stephan Herrera
Published online: 21 June 2004 | doi:10.1038/nbt0704-792
Full text | PDF (147K)
Europe makes way into structural biology p793
Sally Goodman
Published online: 21 June 2004 | doi:10.1038/nbt0704-793
Full text | PDF (285K)
In Brief
News In Brief pp795 - 797
doi:10.1038/nbt0704-795
Full text | PDF (191K)
Data Page
State of the biotech sector p798
Stacy Lawrence
doi:10.1038/nbt0704-798
Full text | PDF (45K)
News Feature
DNA vaccines—back in the saddle again? pp799 - 801
Kendall Powell
doi:10.1038/nbt0704-799
Abstract | Full text | PDF (175K)
Opinion and Comment Top
Correspondence
Drugs in Mexican crops? p803
Francisca Acevedo
doi:10.1038/nbt0704-803a
Full text | PDF (67K)
The facts on flax p803
Joe Cummins
doi:10.1038/nbt0704-803b
Full text | PDF (67K)
Schmeiser versus Monsanto pp803 - 804
Konrad Sechley
doi:10.1038/nbt0704-803c
Full text | PDF (76K)
Stem cell differentiation pp804 - 805
Ali Salim, Amato J. Giaccia & Michael T. Longaker
doi:10.1038/nbt0704-804
Full text | PDF (129K)
Response to Stem cell differentiation pp805 - 806
Jeffrey Rothstein & Evan Snyder
doi:10.1038/nbt0704-805
Full text | PDF (130K)
Commentary
Public-private collaborations and the race to sequence Agrobacterium tumefaciens pp807 - 810
Mark Harvey & Andrew McMeekin
doi:10.1038/nbt0704-807
Full text | PDF (148K)
The Cartagena Protocol and the future of agbiotech pp811 - 812
Willy De Greef
doi:10.1038/nbt0704-811
Full text | PDF (274K)
Investor's Lab
Bargains in the basement p813
Tom Jacobs
doi:10.1038/nbt0704-813
Full text | PDF (59K)
Book Review
Iconoclast to the Max pp815 - 816
Reviewed by: George L Gabor Miklos
doi:10.1038/nbt0704-815
Full text | PDF (101K)
Feature Top
Valuing the product development cycle in agricultural biotechnology—what's in a name? pp817 - 822
David McElroy
doi:10.1038/nbt0704-817
Abstract | Full text | PDF (260K)
News and Views Top
Custom design of metabolism pp823 - 824
James C Liao
doi:10.1038/nbt0704-823
Abstract | Full text | PDF (109K)
See also: Research by Isaacs et al.
The ins and outs of gene expression control pp824 - 826
Francine B Perler
doi:10.1038/nbt0704-824
Abstract | Full text | PDF (245K)
See also: Research by Zeidler et al.
A cool way to make proteins pp826 - 827
Catherine H Schein
doi:10.1038/nbt0704-826
Abstract | Full text | PDF (195K)
See also: Research by Qing et al.
Biomaterials science and high-throughput screening pp828 - 829
Jeffrey A Hubbell
doi:10.1038/nbt0704-828
Abstract | Full text | PDF (227K)
See also: Research by Anderson et al.
Research Highlights p831
doi:10.1038/nbt0704-831
Full text | PDF (92K)
Research Top
Review
A role for chemistry in stem cell biology pp833 - 840
Sheng Ding & Peter G Schultz
Published online: 30 June 2004 | doi:10.1038/nbt987
Abstract | Full text | PDF (1,114K)
Articles
Engineered riboregulators enable post-transcriptional control of gene expression pp841 - 847
Farren J Isaacs, Daniel J Dwyer, Chunming Ding, Dmitri D Pervouchine, Charles R Cantor & James J Collins
Published online: 20 June 2004 | doi:10.1038/nbt986
Abstract | Full text | PDF (204K)  | Supplementary Information
See also: News and Views by Liao
Para-position derivatives of fungal anthelmintic cyclodepsipeptides engineered with Streptomyces venezuelae antibiotic biosynthetic genes pp848 - 855
Koji Yanai, Naomi Sumida, Kaoru Okakura, Tatsuki Moriya, Manabu Watanabe & Takeshi Murakami
Published online: 06 June 2004 | doi:10.1038/nbt978
Abstract | Full text | PDF (219K)
Single-chain antibodies against a plant viral RNA-dependent RNA polymerase confer virus resistance pp856 - 862
KaJohn Boonrod, Danuta Galetzka, Peter D Nagy, Udo Conrad & Gabi Krczal
Published online: 13 June 2004 | doi:10.1038/nbt983
Abstract | Full text | PDF (943K)
Letters
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells pp863 - 866
Daniel G Anderson, Shulamit Levenberg & Robert Langer
Published online: 13 June 2004 | doi:10.1038/nbt981
Abstract | Full text | PDF (1,953K)  | Supplementary Information
See also: News and Views by Hubbell
An engineered epigenetic transgene switch in mammalian cells pp867 - 870
Beat P Kramer, Alessandro Usseglio Viretta, Marie Daoud-El Baba, Dominique Aubel, Wilfried Weber & Martin Fussenegger
Published online: 06 June 2004 | doi:10.1038/nbt980
Abstract | Full text | PDF (162K)
Temperature-sensitive control of protein activity by conditionally splicing inteins pp871 - 876
Martin P Zeidler, Change Tan, Yohanns Bellaiche, Sara Cherry, Sabine Häder, Urte Gayko & Norbert Perrimon
Published online: 06 June 2004 | doi:10.1038/nbt979
Abstract | Full text | PDF (1,266K)  | Supplementary Information
See also: News and Views by Perler
Cold-shock induced high-yield protein production in Escherichia coli pp877 - 882
Guoliang Qing, Li-Chung Ma, Ahmad Khorchid, G V T Swapna, Tapas K Mal, Masanori Mitta Takayama, Bing Xia, Sangita Phadtare, Haiping Ke, Thomas Acton, Gaetano T Montelione, Mitsuhiko Ikura & Masayori Inouye
Published online: 13 June 2004 | doi:10.1038/nbt984
Abstract | Full text | PDF (1,350K)  | Supplementary Information
See also: News and Views by Schein
Homogeneous detection of unamplified genomic DNA sequences based on colorimetric scatter of gold nanoparticle probes pp883 - 887
James J Storhoff, Adam D Lucas, Viswanadham Garimella, Y Paul Bao & Uwe R Müller
Published online: 30 May 2004 | doi:10.1038/nbt977
Abstract | Full text | PDF (541K)
A tethered catalysis, two-hybrid system to identify protein-protein interactions requiring post-translational modifications pp888 - 892
Dawei Guo, Tony R Hazbun, Xin-Jing Xu, Sze-Ling Ng, Stanley Fields & Min-Hao Kuo
Published online: 20 June 2004 | doi:10.1038/nbt985
Abstract | Full text | PDF (1,197K)  | Supplementary Information
Ex planta phytoremediation of trichlorophenol and phenolic allelochemicals via an engineered secretory laccase pp893 - 897
Guo-Dong Wang, Qian-Jin Li, Bin Luo & Xiao-Ya Chen
Published online: 13 June 2004 | doi:10.1038/nbt982
Abstract | Full text | PDF (1,074K)  | Supplementary Information
Errata
Erratum: Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78 p899
Diego Martinez, Luis F Larrondo, Nik Putnam, Maarten D Sollewijn Gelpke, Katherine Huang, Jarrod Chapman, Kevin G Helfenbein, Preethi Ramaiya, J Chris Detter, Frank Larimer, Pedro M Coutinho, Bernard Henrissat, Randy Berka, Dan Cullen & Daniel Rokhsar
doi:10.1038/nbt0704-899a
Full text | PDF (50K)
Corrigenda
Corrigendum: Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78 p899
Diego Martinez, Luis F Larrondo, Nik Putnam, Maarten D Sollewijn Gelpke, Katherine Huang, Jarrod Chapman, Kevin G Helfenbein, Preethi Ramaiya, J Chris Detter, Frank Larimer, Pedro M Coutinho, Bernard Henrissat, Randy Berka, Dan Cullen & Daniel Rokhsar
doi:10.1038/nbt0704-899b
Full text | PDF (50K)
Corrigendum: Intellectual property—the dispute between research institutions and voluntary health agencies p899
Lichtman MA, Hunter MD & Liders GJ
doi:10.1038/nbt0704-899c
Full text | PDF (50K)
Resources Top
Patents
Collaborative research presents special problems for patent seekers pp901 - 902
Leigh W Thorne, Edward R Ergenzinger & W Murray Spruill
doi:10.1038/nbt0704-901
Abstract | Full text | PDF (73K)
Recent patent applications in high-throughput screening p903
doi:10.1038/nbt0704-903
Full text | PDF (33K)
People
People p905
doi:10.1038/nbt0704-905
Full text | PDF (60K)
New on the Market
Drug discovery & development p907
doi:10.1038/nbt0704-907
Full text | PDF (292K)
Computational Biology Top
Primer
What is dynamic programming? pp909 - 910
Sean R Eddy
doi:10.1038/nbt0704-909
Abstract | Full text | PDF (198K)  | Supplementary Information
Analysis
Analysis of genomic context: prediction of functional associations from conserved bidirectionally transcribed gene pairs pp911 - 917
Jan O Korbel, Lars J Jensen, Christian von Mering & Peer Bork
Published online: 30 June 2004 | doi:10.1038/nbt988
Abstract | Full text | PDF (1,429K)  | Supplementary Information
Bioentrepreneur Top
Bioenews
Global biotech expansion taking cues from Bayh-Dole pp919 - 920
Ken Howard
Published online: 20 May 2004 | doi:10.1038/bioent811
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)

PDF (229K)
Building a business
Navigating US conflict-of-interest rules when commercializing research pp921 - 924
John Otrompke
Published online: 25 August 2003 | doi:10.1038/bioent760
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)

PDF (148K)
Naturejobs Top
Careers and Recruitment
Managing your compensation expectations in today's environment: a second look pp925 - 926
John Radford
doi:10.1038/nbt0704-925
Abstract | Full text | PDF (73K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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