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| In This Issue | Top |
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| Editorial | Top |
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Numb and number p785 doi:10.1038/nbt0704-785 Full text | PDF
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| News | Top |
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Celltech acquisition sends mixed messages p787 Peter Mitchell Published online: 21 June 2004 | doi:10.1038/nbt0704-787 Full text | PDF
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Genta sued over NDA withdrawal pp788 - 789 George S. Mack Published online: 21 June 2004 | doi:10.1038/nbt0704-788 Full text | PDF
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E&Y report backs Asia-Pacific biotech pp789 - 790 Sabine Louët doi:10.1038/nbt0704-789 Full text | PDF
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Agbiotech firms realign product focus p791 Jeffrey L Fox Published online: 21 June 2004 | doi:10.1038/nbt0704-791 Full text | PDF
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US rejiggers Bioshield bill p792 Stephan Herrera Published online: 21 June 2004 | doi:10.1038/nbt0704-792 Full text | PDF
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Europe makes way into structural biology p793 Sally Goodman Published online: 21 June 2004 | doi:10.1038/nbt0704-793 Full text | PDF
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| In Brief |
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News In Brief pp795 - 797 doi:10.1038/nbt0704-795 Full text | PDF
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| Data Page |
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State of the biotech sector p798 Stacy Lawrence doi:10.1038/nbt0704-798 Full text | PDF
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| News Feature |
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DNA vaccinesback in the saddle again? pp799 - 801 Kendall Powell doi:10.1038/nbt0704-799 Abstract | Full text | PDF
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| Opinion and Comment | Top |
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| Correspondence |
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Drugs in Mexican crops? p803 Francisca Acevedo doi:10.1038/nbt0704-803a Full text | PDF
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The facts on flax p803 Joe Cummins doi:10.1038/nbt0704-803b Full text | PDF
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Schmeiser versus Monsanto pp803 - 804 Konrad Sechley doi:10.1038/nbt0704-803c Full text | PDF
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Stem cell differentiation pp804 - 805 Ali Salim, Amato J. Giaccia
& Michael T. Longaker doi:10.1038/nbt0704-804 Full text | PDF
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Response to Stem cell differentiation pp805 - 806 Jeffrey Rothstein
& Evan Snyder doi:10.1038/nbt0704-805 Full text | PDF
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| Commentary |
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Public-private collaborations and the race to sequence Agrobacterium tumefaciens pp807 - 810 Mark Harvey
& Andrew McMeekin doi:10.1038/nbt0704-807 Full text | PDF
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The Cartagena Protocol and the future of agbiotech pp811 - 812 Willy De Greef doi:10.1038/nbt0704-811 Full text | PDF
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| Investor's Lab |
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Bargains in the basement p813 Tom Jacobs doi:10.1038/nbt0704-813 Full text | PDF
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| Book Review |
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Iconoclast to the Max pp815 - 816 Reviewed by: George L Gabor Miklos doi:10.1038/nbt0704-815 Full text | PDF
(101K)
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| Feature | Top |
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Valuing the product development cycle in agricultural biotechnologywhat's in a name? pp817 - 822 David McElroy doi:10.1038/nbt0704-817 Abstract | Full text | PDF
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| News and Views | Top |
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Custom design of metabolism pp823 - 824 James C Liao doi:10.1038/nbt0704-823 Abstract | Full text | PDF
(109K)
See also: Research by Isaacs et al. |
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The ins and outs of gene expression control pp824 - 826 Francine B Perler doi:10.1038/nbt0704-824 Abstract | Full text | PDF
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See also: Research by Zeidler et al. |
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A cool way to make proteins pp826 - 827 Catherine H Schein doi:10.1038/nbt0704-826 Abstract | Full text | PDF
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See also: Research by Qing et al. |
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Biomaterials science and high-throughput screening pp828 - 829 Jeffrey A Hubbell doi:10.1038/nbt0704-828 Abstract | Full text | PDF
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See also: Research by Anderson et al. |
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Research Highlights p831 doi:10.1038/nbt0704-831 Full text | PDF
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| Research | Top |
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| Review |
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A role for chemistry in stem cell biology pp833 - 840 Sheng Ding
& Peter G Schultz Published online: 30 June 2004 | doi:10.1038/nbt987 Abstract | Full text | PDF
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| Articles |
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Engineered riboregulators enable post-transcriptional control of gene expression pp841 - 847 Farren J Isaacs, Daniel J Dwyer, Chunming Ding, Dmitri D Pervouchine, Charles R Cantor
& James J Collins Published online: 20 June 2004 | doi:10.1038/nbt986 Abstract | Full text | PDF
(204K)
| Supplementary Information See also: News and Views by Liao |
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Para-position derivatives of fungal anthelmintic cyclodepsipeptides engineered with Streptomyces venezuelae antibiotic biosynthetic genes pp848 - 855 Koji Yanai, Naomi Sumida, Kaoru Okakura, Tatsuki Moriya, Manabu Watanabe
& Takeshi Murakami Published online: 06 June 2004 | doi:10.1038/nbt978 Abstract | Full text | PDF
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Single-chain antibodies against a plant viral RNA-dependent RNA polymerase confer virus resistance pp856 - 862 KaJohn Boonrod, Danuta Galetzka, Peter D Nagy, Udo Conrad
& Gabi Krczal Published online: 13 June 2004 | doi:10.1038/nbt983 Abstract | Full text | PDF
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| Letters |
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Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells pp863 - 866 Daniel G Anderson, Shulamit Levenberg
& Robert Langer Published online: 13 June 2004 | doi:10.1038/nbt981 Abstract | Full text | PDF
(1,953K)
| Supplementary Information See also: News and Views by Hubbell |
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An engineered epigenetic transgene switch in mammalian cells pp867 - 870 Beat P Kramer, Alessandro Usseglio Viretta, Marie Daoud-El Baba, Dominique Aubel, Wilfried Weber
& Martin Fussenegger Published online: 06 June 2004 | doi:10.1038/nbt980 Abstract | Full text | PDF
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Temperature-sensitive control of protein activity by conditionally splicing inteins pp871 - 876 Martin P Zeidler, Change Tan, Yohanns Bellaiche, Sara Cherry, Sabine Häder, Urte Gayko
& Norbert Perrimon Published online: 06 June 2004 | doi:10.1038/nbt979 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Perler |
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Cold-shock induced high-yield protein production in Escherichia coli pp877 - 882 Guoliang Qing, Li-Chung Ma, Ahmad Khorchid, G V T Swapna, Tapas K Mal, Masanori Mitta Takayama, Bing Xia, Sangita Phadtare, Haiping Ke, Thomas Acton, Gaetano T Montelione, Mitsuhiko Ikura
& Masayori Inouye Published online: 13 June 2004 | doi:10.1038/nbt984 Abstract | Full text | PDF
(1,350K)
| Supplementary Information See also: News and Views by Schein |
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Homogeneous detection of unamplified genomic DNA sequences based on colorimetric scatter of gold nanoparticle probes pp883 - 887 James J Storhoff, Adam D Lucas, Viswanadham Garimella, Y Paul Bao
& Uwe R Müller Published online: 30 May 2004 | doi:10.1038/nbt977 Abstract | Full text | PDF
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A tethered catalysis, two-hybrid system to identify protein-protein interactions requiring post-translational modifications pp888 - 892 Dawei Guo, Tony R Hazbun, Xin-Jing Xu, Sze-Ling Ng, Stanley Fields
& Min-Hao Kuo Published online: 20 June 2004 | doi:10.1038/nbt985 Abstract | Full text | PDF
(1,197K)
| Supplementary Information |
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Ex planta phytoremediation of trichlorophenol and phenolic allelochemicals via an engineered secretory laccase pp893 - 897 Guo-Dong Wang, Qian-Jin Li, Bin Luo
& Xiao-Ya Chen Published online: 13 June 2004 | doi:10.1038/nbt982 Abstract | Full text | PDF
(1,074K)
| Supplementary Information |
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| Errata |
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Erratum: Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78 p899 Diego Martinez, Luis F Larrondo, Nik Putnam, Maarten D Sollewijn Gelpke, Katherine Huang, Jarrod Chapman, Kevin G Helfenbein, Preethi Ramaiya, J Chris Detter, Frank Larimer, Pedro M Coutinho, Bernard Henrissat, Randy Berka, Dan Cullen
& Daniel Rokhsar doi:10.1038/nbt0704-899a Full text | PDF
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| Corrigenda |
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Corrigendum: Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78 p899 Diego Martinez, Luis F Larrondo, Nik Putnam, Maarten D Sollewijn Gelpke, Katherine Huang, Jarrod Chapman, Kevin G Helfenbein, Preethi Ramaiya, J Chris Detter, Frank Larimer, Pedro M Coutinho, Bernard Henrissat, Randy Berka, Dan Cullen
& Daniel Rokhsar doi:10.1038/nbt0704-899b Full text | PDF
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Corrigendum: Intellectual propertythe dispute between research institutions and voluntary health agencies p899 Lichtman MA, Hunter MD
& Liders GJ doi:10.1038/nbt0704-899c Full text | PDF
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| Resources | Top |
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| Patents |
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Collaborative research presents special problems for patent seekers pp901 - 902 Leigh W Thorne, Edward R Ergenzinger
& W Murray Spruill doi:10.1038/nbt0704-901 Abstract | Full text | PDF
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Recent patent applications in high-throughput screening p903 doi:10.1038/nbt0704-903 Full text | PDF
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| People |
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People p905 doi:10.1038/nbt0704-905 Full text | PDF
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| New on the Market |
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Drug discovery & development p907 doi:10.1038/nbt0704-907 Full text | PDF
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| Computational Biology | Top |
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| Primer |
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What is dynamic programming? pp909 - 910 Sean R Eddy doi:10.1038/nbt0704-909 Abstract | Full text | PDF
(198K)
| Supplementary Information |
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| Analysis |
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Analysis of genomic context: prediction of functional associations from conserved bidirectionally transcribed gene pairs pp911 - 917 Jan O Korbel, Lars J Jensen, Christian von Mering
& Peer Bork Published online: 30 June 2004 | doi:10.1038/nbt988 Abstract | Full text | PDF
(1,429K)
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| Bioentrepreneur | Top |
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| Bioenews |
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Global biotech expansion taking cues from Bayh-Dole pp919 - 920 Ken Howard Published online: 20 May 2004 | doi:10.1038/bioent811 Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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| Building a business |
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Navigating US conflict-of-interest rules when commercializing research pp921 - 924 John Otrompke Published online: 25 August 2003 | doi:10.1038/bioent760 Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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(148K)
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| Naturejobs | Top |
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| Careers and Recruitment |
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Managing your compensation expectations in today's environment: a second look pp925 - 926 John Radford doi:10.1038/nbt0704-925 Abstract | Full text | PDF
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