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Volume 19 Issue 8, August 2001

A representation of protein translation in vitro. The details, see Ueda et al. (p. 751). Graphic by Ken Eward of BioGrafx.

Editorial

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Correspondence

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Feature

  • Rapidly resolving the pharmacokinetic and toxicological properties of drug candidates remains a key challenge for drug developers.

    • John Hodgson
    Feature
  • Despite the advent of new science and technologies, drug developers will need to make radical changes in their operations if they are to remain competitive and innovative.

    • Scott Myers
    • Ann Baker
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News & Views

  • A variation on an approach that uses diphtheria toxin to ablate specific cells in mice provides a better means of assessing biological function.

    • Richard Palmiter
    News & Views
  • In vitro protein synthesis using a mixture of purified components now offers the possibility of efficient production of labile products and more detailed study of the translation process.

    • James Swartz
    News & Views
  • Peptides derived from tiny bacterial viruses may offer an alternative strategy for combating bacterial infections.

    • Vincent A. Fischetti
    News & Views
  • Transgenic plants expressing an enzyme that degrades microbial signaling molecules show promise in controlling damage caused by bacterial infections.

    • Neil A. Whitehead
    • Martin Welch
    • George P.C. Salmond
    News & Views
  • Slowly, more information is emerging about the function of untranslated RNAs in regulating transcript maturation and splicing.

    • C.A. Stein
    News & Views
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