Industry Trends


Nature Biotechnology 15, 479 - 480 (1997)
doi:10.1038/nbt0597-479

The carbohydrate-based drug industry

Aris Persidis1


Whether used as a target or a tool carbohydrates face manufacturing challenges before they can realize their true value.

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  1. 1Aris Persidis is vice president for business development, Argonex Inc., 2044 India Road, Charlottesville, VA 22901 (apersidis@argonex. com).



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Industry Trends
Nature Biotechnology  15, 479 - 480 (1997)
doi:10.1038/nbt0597-479

The carbohydrate-based drug industry

Aris Persidis1

1Aris Persidis is vice president for business development, Argonex Inc., 2044 India Road, Charlottesville, VA 22901 (apersidis@argonex. com).

Whether used as a target or a tool carbohydrates face manufacturing challenges before they can realize their true value.

REFERENCES
    1. Dwek, R.A.1996. Glycobiology: Toward understanding the function of sugars. Chem. Rev.96: 683–720. | Article | PubMed | ISI | ChemPort |
    2. Frechet, J.M. and Schuerch, C.1971. Solid-phase tri-saccharide synthesis. J. Am. Chem. Soc.93: 492–496. | ISI |
    3. Bednarski, M. and Simon, E.S. (eds.). 1991. Enzymes in Carbohydrate Synthesis, ACS Series 446. American Chemical Society, Washington, DC.
    4. Borman, S.1994. Chemical-enzymatic technique used to make carbohydrates, glycopeptides. Chem. Eng. News7237–39. | ISI |
    5. Borman, S.Review & Company Database: Carbohydrate Therapeutics—1997. Edition. ASSETT, e-mail: assettnetor.gr.
    6. Boons, G-T.1996. Synthetic oligosaccharides: Recent advances. Drug Dev. Today.1: 331–342. | Article | ChemPort |
    7. Persidis, A.1995. Enabling technologies and the business of science. Bio/Technology13: 1172–1176. | ISI | ChemPort |
    8. These companies are Alpha-Beta Technology, Biomira, Cytel, Glycomed, Ligand Pharmaceuticals, Martek, Neose Technologies, and Oxford GlycoSciences.
    9. Persidis, A.1997. Industry trends: Combinatorial chemistry. Nature Biotechnology15: 391–393. | Article | ISI | ChemPort |
    10. Rouhi, M.1996. Carbohydrates combinatorially. Chem. Eng. News 74: 4.
  1. Dwek, R.A. 1996. Glycobiology: Toward understanding the function of sugars. Chem. Rev. 96: 683−720.
  2. Frechet, J.M. and Schuerch, C. 1971. Solid-phase tri-saccharide synthesis. J. Am. Chem. Soc. 93: 492−496.
  3. Bednarski, M. and Simon, E.S. (eds.). 1991. Enzymes in Carbohydrate Synthesis, ACS Series 446. American Chemical Society, Washington, DC.
  4. Borman, S. 1994. Chemical-enzymatic technique used to make carbohydrates, glycopeptides. Chem. Eng. News 72 37−39.
  5. Borman, S.Review & Company Database: Carbohydrate Therapeutics—1997. Edition. ASSETT, e-mail: assettnetor.gr.
  6. Boons, G-T. 1996. Synthetic oligosaccharides: Recent advances. Drug Dev. Today. 1: 331−342.
  7. Persidis, A. 1995. Enabling technologies and the business of science. Bio/Technology 13: 1172−1176.
  8. These companies are Alpha-Beta Technology, Biomira, Cytel, Glycomed, Ligand Pharmaceuticals, Martek, Neose Technologies, and Oxford GlycoSciences.
  9. Persidis, A. 1997. Industry trends: Combinatorial chemistry. Nature Biotechnology 15: 391−393.
  10. Rouhi, M. 1996. Carbohydrates combinatorially. Chem. Eng. News 74: 4.
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